The multidisciplinary management of rectal cancer
نویسندگان
چکیده
منابع مشابه
Multidisciplinary management of resectable rectal cancer.
The standard adjuvant therapy for resectable T3 and/or N1-2 rectal cancer is pelvic radiation therapy plus fluorouracil (5-FU)-based chemotherapy. Two randomized intergroup trials, INT 0114 and INT 0144, will help determine the ideal chemotherapeutic agents and their routes of administration in the postoperative setting. The randomized National Surgical Adjuvant Project for Breast and Bowel Can...
متن کاملMultidisciplinary management of early-stage rectal cancer.
Because patients with locally advanced rectal cancer are at high risk for both recurrence and distant disease, they require adjuvant therapy. In the United States, the current standard of care is neoadjuvant chemoradiation followed by surgery and adjuvant chemotherapy. Neoadjuvant chemoradiation has been shown to improve local recurrence rates and decrease toxicity. However in the era of total ...
متن کاملThe importance of a multidisciplinary team in rectal cancer management
INTRODUCTION The aim of this study was to evaluate the impact of the interval between surgery and adjuvant treatments regarding the overall survival and recurrence-free survival in patients from a developing country. For stages II and III rectal cancer, international guidelines recommend neoadjuvant chemoradiotherapy (CRT) regardless of the tumor location. In the developing countries there is a...
متن کاملMultidisciplinary management of patients with advanced rectal cancer.
The chance of lymph node involvement in T(3) and T(4) rectal cancers is 20% to 60%, a risk sufficiently high that most clinicians favor mesorectal excision rather than less aggressive approaches. Patients who have a complete clinical response of the primary lesions to neoadjuvant therapy may represent a special case. Total mesorectal excision can be accomplished without sacrifice of the anal sp...
متن کاملThe multidisciplinary treatment of rectal cancer: pathology.
In the multidisciplinary treatment of rectal cancer various disciplines are involved to make treatment decisions. Pathology is one of them, being involved in both preoperative and postoperative patient evaluation. In the current review the preoperative role is described briefly and it focuses mainly on the postoperative evaluation. This evaluation is not only the assessment of tumour invasion, ...
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ژورنال
عنوان ژورنال: Nature Reviews Gastroenterology & Hepatology
سال: 2020
ISSN: 1759-5045,1759-5053
DOI: 10.1038/s41575-020-0275-y